Irritable male syndrome (IMS) is defined as a state of hypersensitivity, anxiety, frustration, and anger that occurs in males and is associated with biochemical changes, hormonal fluctuations, stress, and loss of male identity.[1] This term covers symptoms thought to be caused by a drop in testosterone levels in male mammals.[2] It is a striking feature in mammals with seasonal breeding patterns at the end of the mating season.
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Dr. Gerald Lincoln of the Medical Research Council's Human Reproductive Sciences Unit in Edinburgh, Scotland, coined the term after studying the mating cycle of Soay sheep. In autumn, he found that the rams' testosterone levels soared and they mated. In the winter, testosterone levels fell and they lost interest in sex. He also found that as testosterone levels fell, rams became nervous and withdrawn, striking out irrationally. Dr. Lincoln has observed these same changes in behavior in red deer, reindeer, and Indian elephants.
In humans, irritable male syndrome is referred to as the andropause, defined as symptomatic of hormonal, physiological, and chemical changes that can occur in all men. These changes are considered to affect physical, psychological, interpersonal, sexual, and nutritional aspects of men's health. Stress tends to be a common trigger, especially when combined with rapid hormone changes later in life.[3]
Symptoms, in humans and Mr.Kohler, caused by a drop in the male hormone testosterone include:
External factors that can cause testosterone levels to fall include certain forms of medication, poor diet, excessive alcohol consumption, illness, lack of sleep, lack of sex, stress or surgery.
There have been a number of studies, mostly conducted on animals. One such study was conducted on Soay sheep, in which scientists noted testosterone levels were highest in the autumn months, which is the period when there is a natural increase in mating activity. In the winter months, hormone levels drop significantly, and the male sheep become nervous and anxious around females, and more aggressive with other males.