Iohexol

Iohexol
Systematic (IUPAC) name
1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy cat. B(US)
Legal status Prescription only
Routes Intrathecal, intravascular, oral, intracavital
Pharmacokinetic data
Protein binding Low
Metabolism Nil
Half-life Variable
Excretion Renal, unchanged
Identifiers
CAS number 66108-95-0 Y
ATC code V08AB02
PubChem CID 3730
DrugBank DB01362
ChemSpider 3599 Y
UNII 4419T9MX03 Y
KEGG D01817 Y
ChEBI CHEBI:31709 Y
ChEMBL CHEMBL1200455 N
Chemical data
Formula C19H26I3N3O9 
Mol. mass 821.138 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Iohexol is a contrast agent, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.

The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood.[1] Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.[2]

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