Idraparinux

Idraparinux
Systematic (IUPAC) name
Nonasodium (2S,3S,4S,5R,6R)-6-[(2R,3R,4S,5R,6R)-6-
Clinical data
Pregnancy cat.  ?
Legal status Investigational
Routes Subcutaneous
Pharmacokinetic data
Half-life 80-130 hours
Identifiers
CAS number 149920-56-9 Y
ATC code None
PubChem CID 3083444
ChemSpider 2340656 Y
Chemical data
Formula C38H55Na9O49S7 
Mol. mass 1727.17683 g/mol
SMILES eMolecules & PubChem
 Y(what is this?)  (verify)

Idraparinux sodium is an anticoagulant medication in development by Sanofi-Aventis.[1]

It has a similar chemical structure and the same method of action as fondaparinux, but with an elimination half-life about five to six times longer (an increase from fondaparinux's 17 hours to approximately 80 hours), which means that the drug should only need to be injected once a week.

As of July 2007, it has completed the Phase III clinical trial AMADEUS.

Method of action

Idraparinux selectively blocks coagulation factor Xa.[2]

See Heparin: Mechanism of anticoagulant action for a comparison of the mechanism of heparin, low-molecular-weight heparins, fondaparinux and idraparinux.

References