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(1) Basic domains
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Activating transcription factor ( AATF, 1, 2, 3, 4, 5, 6, 7) ยท AP-1 ( c-Fos, FOSB, FOSL1, FOSL2, JDP2, c-Jun, JUNB, JUND) ยท BACH ( 1, 2) ยท BATF ยท BLZF1 ยท C/EBP ( ฮฑ, ฮฒ, ฮณ, ฮด, ฮต, ฮถ) ยท CREB ( 1, 3, L1) ยท CREM ยท DBP ยท DDIT3 ยท GABPA ยท HLF ยท MAF ( B, F, G, K) ยท NFE ( 2, L1, L2, L3) ยท NFIL3 ยท NRL ยท NRF ( 1, 2, 3) ยท XBP1
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(1.2) Basic helix-loop-helix ( bHLH)
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ATOH1 ยท AhR ยท AHRR ยท ARNT ยท ASCL1 ยท BHLHB2 ยท BMAL ( ARNTL, ARNTL2) ยท CLOCK ยท EPAS1 ยท FIGLA ยท HAND ( 1, 2) ยท HES ( 5, 6) ยท HEY ( 1, 2, L) ยท HES1 ยท HIF ( 1A, 3A) ยท ID ( 1, 2, 3, 4) ยท LYL1 ยท MESP2 ยท MXD4 ยท MYCL1 ยท MYCN ยท Myogenic regulatory factors ( MyoD, Myogenin, MYF5, MYF6) ยท Neurogenins ( 1, 2, 3) ยท NeuroD ( 1, 2) ยท NPAS ( 1, 2, 3) ยท OLIG ( 1, 2) ยท Pho4 ยท Scleraxis ยท SIM ( 1, 2) ยท TAL ( 1, 2) ยท Twist ยท USF1
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(1.4) NF-1
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(1.5) RF-X
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(1.6) Basic helix-span-helix (bHSH)
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subfamily 1 ( Thyroid hormone ( ฮฑ, ฮฒ), CAR, FXR, LXR ( ฮฑ, ฮฒ), PPAR ( ฮฑ, ฮฒ/ฮด, ฮณ), PXR, RAR ( ฮฑ, ฮฒ, ฮณ), ROR ( ฮฑ, ฮฒ, ฮณ), Rev-ErbA ( ฮฑ, ฮฒ), VDR)
subfamily 2 ( COUP-TF ( I, II), Ear-2, HNF4 ( ฮฑ, ฮณ), PNR, RXR ( ฮฑ, ฮฒ, ฮณ), Testicular receptor ( 2, 4), TLX)
subfamily 3 ( Steroid hormone ( Androgen, Estrogen ( ฮฑ, ฮฒ), Glucocorticoid, Mineralocorticoid, Progesterone), Estrogen related ( ฮฑ, ฮฒ, ฮณ))
subfamily 4 NUR ( NGFIB, NOR1, NURR1) ยท subfamily 5 ( LRH-1, SF1) ยท subfamily 6 ( GCNF) ยท subfamily 0 ( DAX1, SHP)
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(2.2) Other Cys4
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(2.3) Cys2His2
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General transcription factors ( TFIIA, TFIIB, TFIID, TFIIE ( 1, 2), TFIIF ( 1, 2), TFIIH ( 1, 2, 4, 2I, 3A, 3C1, 3C2))
ATBF1 ยท BCL ( 6, 11A, 11B) ยท CTCF ยท E4F1 ยท EGR ( 1, 2, 3, 4) ยท ERV3 ยท GFI1 ยท GLI-Krรผppel family ( 1, 2, 3, REST, S2, YY1) ยท HIC ( 1, 2) ยท HIVEP ( 1, 2, 3) ยท IKZF ( 1, 2, 3) ยท ILF ( 2, 3) ยท KLF ( 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17) ยท MTF1 ยท MYT1 ยท OSR1 ยท PRDM9 ยท SALL ( 1, 2, 3, 4) ยท SP ( 1, 2, 4, 7, 8) ยท TSHZ3 ยท WT1 ยท Zbtb7 ( 7A, 7B) ยท ZBTB ( 16, 17, 20, 32, 33, 40) ยท zinc finger ( 3, 7, 9, 10, 19, 22, 24, 33B, 34, 35, 41, 43, 44, 51, 74, 143, 146, 148, 165, 202, 217, 219, 238, 239, 259, 267, 268, 281, 295, 300, 318, 330, 346, 350, 365, 366, 384, 423, 451, 452, 471, 593, 638, 644, 649, 655)
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(2.4) Cys6
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(2.5) Alternating composition
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ARX ยท CDX ( 1, 2) ยท CRX ยท CUTL1 ยท DBX ( 1, 2) ยท DLX ( 3, 4, 5) ยท EMX2 ยท EN ( 1, 2) ยท FHL ( 1, 2, 3) ยท HESX1 ยท HHEX ยท HLX ยท Homeobox ( A1, A2, A3, A4, A5, A7, A9, A10, A11, A13, B1, B2, B3, B4, B5, B6, B7, B8, B9, B13, C4, C5, C6, C8, C9, C10, C11, C12, C13, D1, D3, D4, D8, D9, D10, D11, D12, D13) ยท HOPX ยท IRX (1, 2, 3, 4, 5, 6, MKX) ยท LMX ( 1A, 1B) ยท MEIS ( 1, 2) ยท MEOX2 ยท MNX1 ยท MSX ( 1, 2) ยท NANOG ยท NKX ( 2-1, 2-2, 2-3, 2-5, 3-1, 3-2, 6-1, 6-2) ยท NOBOX ยท PBX ( 1, 2, 3) ยท PHF ( 1, 3, 6, 8, 10, 16, 17, 20, 21A) ยท PHOX ( 2A, 2B) ยท PITX ( 1, 2, 3) ยท POU domain ( PIT-1, BRN-3: A, B, C, Octamer transcription factor: 1, 2, 3/4, 6, 7, 11) ยท OTX ( 1, 2) ยท PDX1 ยท SATB2 ยท SHOX2 ยท VAX1 ยท ZEB ( 1, 2)
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(3.2) Paired box
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E2F ( 1, 2, 3, 4, 5) ยท FOX proteins ( A1, A2, A3, C1, C2, D3, D4, E1, E3, F1, G1, H1, I1, J1, J2, K1, K2, L2, M1, N1, N3, O1, O3, O4, P1, P2, P3, P4)
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(3.5) Tryptophan clusters
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ELF ( 2, 4, 5) ยท EGF ยท ELK ( 1, 3, 4) ยท ERF ยท ETS ( 1, 2, ERG, SPIB) ยท ETV ( 1, 4, 5, 6) ยท FLI1 ยท Interferon regulatory factors ( 1, 2, 3, 4, 5, 6, 7, 8) ยท MYB ยท MYBL2
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(3.6) TEA domain
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transcriptional enhancer factor ( 1, 2, 3, 4)
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(4) ฮฒ-Scaffold factors with minor groove contacts
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(4.3) p53
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BBX ยท HMGB ( 1, 2, 3, 4) ยท HMGN ( 1, 2, 3, 4) ยท HNF ( 1A, 1B) ยท LEF1 ยท SOX ( 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 18, 21) ยท SRY ยท SSRP1 ยท TCF ( 3, 4) ยท TOX ( 1, 2, 3, 4)
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(4.10) Cold-shock domain
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(4.11) Runt
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(0) Other transcription factors
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(0.2) HMGI(Y)
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(0.6) Miscellaneous
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ARID ( 1A, 1B, 2, 3A, 3B, 4A) ยท CAP ยท IFI ( 16, 35) ยท MLL ( 2, 3, T1) ยท MNDA ยท NFY ( A, B, C) ยท Rho/ Sigma
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see also transcription factor/coregulator deficiencies
B bsyn: dna (repl, cycl, reco, repr) ยท tscr (fact, tcrg, nucl, rnat, rept, ptts) ยท tltn (risu, pttl, nexn) ยท dnab, rnab/runp ยท stru (domn, 1ยฐ, 2ยฐ, 3ยฐ, 4ยฐ)
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