IPO9

Importin 9

Identifiers

IPO9; DKFZp761M1547; FLJ10402; Imp9

External IDs

MGI: 1918944 HomoloGene: 5874 GeneCards: IPO9 Gene

Gene Ontology
Molecular function	• protein binding • protein transporter activity • histone binding
Cellular component	• nucleus • cytoplasm
Biological process	• protein import into nucleus • intracellular protein transport • protein transport
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000198700

ENSMUSG00000041879

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 1:
201.8 – 201.85 Mb

Chr 1:
137.28 – 137.33 Mb

PubMed search

Importin-9 is a protein that in humans is encoded by the IPO9 gene.^[1]^[2]^[3]

References

^ Jakel S, Mingot JM, Schwarzmaier P, Hartmann E, Gorlich D (Feb 2002). "Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains". EMBO J 21 (3): 377–86. doi:10.1093/emboj/21.3.377. PMC 125346. PMID 11823430. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=125346.
^ Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
^ "Entrez Gene: IPO9 importin 9". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55705.

Further reading

Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310934.
Mühlhäusser P, Müller EC, Otto A, Kutay U (2001). "Multiple pathways contribute to nuclear import of core histones". EMBO Rep. 2 (8): 690–6. doi:10.1093/embo-reports/kve168. PMC 1084005. PMID 11493596. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1084005.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Lubert EJ, Sarge KD (2003). "Interaction between protein phosphatase 2A and members of the importin beta superfamily". Biochem. Biophys. Res. Commun. 303 (3): 908–13. doi:10.1016/S0006-291X(03)00434-0. PMID 12670497.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129.