| Interleukin 36, gamma | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | IL36G; IL-1F9; IL-1H1; IL-1RP2; IL1E; IL1F9; IL1H1; IL1RP2 | ||||||||||||
| External IDs | OMIM: 605542 MGI: 2449929 HomoloGene: 49595 GeneCards: IL36G Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 56300 | 215257 | |||||||||||
| Ensembl | ENSG00000136688 | ENSMUSG00000044103 | |||||||||||
| UniProt | Q9NZH8 | Q14BB6 | |||||||||||
| RefSeq (mRNA) | NM_019618 | NM_153511.3 | |||||||||||
| RefSeq (protein) | NP_062564 | NP_705731.2 | |||||||||||
| Location (UCSC) | Chr 2: 113.73 – 113.74 Mb |
Chr 2: 24.04 – 24.05 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Interleukin-1 family member 9 is a protein that in humans is encoded by the IL1F9 gene.[1][2][3][4][5]
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.[5]
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