Hypoalphalipoproteinemia | |
---|---|
Classification and external resources | |
ICD-10 | E78.6 |
ICD-9 | 272.5 |
OMIM | 604091 |
eMedicine | med/3368 |
MeSH | D052456 |
Hypoalphalipoproteinemia is a high-density lipoprotein deficiency, inherited in an autosomal dominant manner.[1]
It can be associated with LDL receptor.[2]
Associated regions and genes include:
Name | OMIM | Locus | Candidates |
---|---|---|---|
HDLCQ1 | 606613 | 9p | ABCA1 (Tangier disease)[3] |
HDLCQ2 | 607053 | 8q23 | |
HDLCQ3 | 607687 | 16q24.1 | LCAT (Lecithin cholesterol acyltransferase deficiency) |
HDLCQ4 | 610239 | 4q32 | |
HDLD3 | 605201 | 11q23.3 | APOA1 |
Niacin is sometimes prescribed to raise HDL levels.