Hyalobarrier

Hyalobarrier is a substance to keep tissue apart post surgery and therefore prevent adhesions. It contains autocross-linked hyaluronan. Highly viscous due to condensation. Hyaluronan is present in cartilage and skin hence there is a natural metabolic pathway for it. This gel is used to separate organs and tissue after surgery. Scientific documentation so far covers the gynaecology speciality. IE Laparoscopic surgery, hysteroscopy/hysteroscopic surgery but also open surgery. According to data in a Cochrane collaboration review active action to prevent adhesions needs to be taken to a larger extent. The Cochrane report also states that the incidence of postsurgical adhesions is as high as 60 to 90%.[1] In a recent review by C Sutton (University of Surrey, Guilford UK), it is stated that Hyalobarrier is the only anti adhesive substance that has published data for intrauterine use.[2]

Additional information

References

  1. ^ Ahmad G, Duffy JM, Farquhar C, et al. (2008). "Barrier agents for adhesion prevention after gynaecological surgery". Cochrane Database Syst Rev (2): CD000475. doi:10.1002/14651858.CD000475.pub2. PMID 18425865. http://www.cochrane.org/reviews/en/ab000475.html. 
  2. ^ Sutton C (2009). "Adhesions following surgery: pathogenesis and current experience with adhesion barriers". Surg Technol Int 18: 144–56. PMID 19579202.