Hispidin

Hispidin
IUPAC name

2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxypyran-4-one
Other names

6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone
Identifiers
CAS number 555-55-5 Y=
PubChem 5353671
Jmol-3D images Image 1
Properties
Molecular formula C13H10O5
Molar mass 246.21 g/mol
Exact mass 246.052823 u
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Hispidin is a natural substance. It can also be synthetised.[1]

Hispidin 4-O-β-d-glucopyranoside can be found in Pteris ensiformis[2] whereas hispidin derivatives can be found in the edible mushroom Inonotus xeranticus[3] or Phellinus.[4]

References

  1. ^ Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro. Gonindard C, Bergonzi C, Denier C, Sergheraert C, Klaebe A, Chavant L and Hollande E, Cell Biol Toxicol. 1997 Mar, 13(3), pp. 141-153, PubMed, doi:10.1023/A:1007321227010
  2. ^ Identification of phenolic antioxidants from Sword Brake fern (Pteris ensiformis Burm.). Yung-Husan Chen, Fang-Rong Chang, Yih-Jer Lin, Lisu Wang, Jinn-Fen Chen, Yang-Chang Wu and Ming-Jiuan Wu, Food Chemistry Volume 105, Issue 1, 2007, pp. 48-56, doi:10.1016/j.foodchem.2007.03.055
  3. ^ Hispidin Derivatives from the Mushroom Inonotus xeranticus and Their Antioxidant Activity. In-Kyoung Lee, Soon-Ja Seok, Wan-Kyu Kim and Bong-Sik Yun, J. Nat. Prod., 2006, 69 (2), pp. 299–301, doi:10.1021/np050453n
  4. ^ Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus. In-Kyoung Lee and Bong-Sik Yu, Bioorganic & Medicinal Chemistry, Volume 15, Issue 10, 15 May 2007, pages 3309-3314, doi:10.1016/j.bmc.2007.03.039