Hemin

For the given name, see Hemin (given name).
Hemin
Systematic (IUPAC) name
chloro[3,7,12,17-tetramethyl-8,13-divinylporphyrin-
2,18-dipropanoato(2−)]iron(III)
Clinical data
AHFS/Drugs.com Consumer Drug Information
Pregnancy cat. C(US)
Legal status ℞-only (US)
Routes Intravenous infusion
Identifiers
CAS number 16009-13-5 Y
ATC code B06AB01
PubChem CID 5318002
ChemSpider 21160444 Y
UNII 743LRP9S7N Y
ChEMBL CHEMBL1628226 N
Chemical data
Formula C34H32ClFeN4O4 
Mol. mass 651.94 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Hemin (trade name Panhematin) is an iron-containing porphyrin.[1] More specifically, it is Protoporphyrin IX containing a ferric iron ion (Heme B) with a chloride ligand.

It is used in the management of porphyria attacks, particularly in acute intermittent porphyria.

It is sometimes distinguished from Hematin which has a hydroxide ligand in place of the chloride. However, the terms are sometimes equated.[2]

Hematin is considered the "X factor" required for the growth of Haemophilus influenzae.[3]

References

  1. ^ "hemin" at Dorland's Medical Dictionary
  2. ^ "hematin" at Dorland's Medical Dictionary
  3. ^ Sherris, John C.; Ryan, Kenneth J.; Ray, C. L. (2004). Sherris medical microbiology: an introduction to infectious diseases. New York: McGraw-Hill. pp. 395. ISBN 0-8385-8529-9. 

External links