The Hamilton Bible (Berlin, Kupferstichkabinett 78 E 3) is a fourteenth-century illuminated manuscript Bible, commissioned by the Angevin court in Naples and illustrated by the workshop of Cristoforo Orimina around 1350.
It was part of the Hamilton Collection of medieval manuscripts, acquired by the Berlin State Library in 1884,[1] and is currently held in the Kupferstichkabinett Berlin, with call number 78 E 3.
It has been thought that the Bible open on the table in Raphael's Portrait of Leo X is the Hamilton Bible.[2]