| Systematic (IUPAC) name | |
|---|---|
| (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydro-1H-benzo[c]chromene-1,4(6H)-dione | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| ATC code | ? |
| PubChem | CID 11370880 |
| ChemSpider | 9545797 |
| Chemical data | |
| Formula | C21H28O3 |
| Mol. mass | 328.445 |
| SMILES | eMolecules & PubChem |
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HU-336 is a strongly antiangiogenic compound, significantly inhibiting angiogenesis at concentrations as low as 300nM. It inhibits angiogenesis by directly inducing apoptosis of vascular endothelial cells without changing the expression of pro- and antiangiogenic cytokines and their receptors. HU-336 is highly effective against tumor xenografts in nude mice.[1]
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