Hereditary motor and sensory neuropathy

Hereditary motor and sensory neuropathy
Classification and external resources
eMedicine	neuro/468
MeSH	D015417

Hereditary motor and sensory neuropathies (HMSN) are a group of neuropathies which are characterized by their impact upon both afferent and efferent neural communication.

They are more common than hereditary sensory and autonomic neuropathies.^[1]

1 Types
2 See also
3 References
4 Further reading

Types

In 1968, it was classified from groups I to VII:^[2]^[3]

Type	Name	Diseases Database	OMIM
I	Charcot-Marie-Tooth disease 1	5815	118220, 118200
II	Charcot-Marie-Tooth disease 2	2343	118210, 600882
III	Dejerine Sottas syndrome	5821	145900
IV	Refsum's disease	11213	266500
V	HMSN+hereditary spastic paraplegia	-	600361
VI	HMSN+hereditary optic atrophy	32095	601152
VII	HMSN+retinitis pigmentosa	32094	-

HMSN is sometimes equated with Charcot-Marie-Tooth disease.^[4]^[5]

References

^ Houlden H, Blake J, Reilly MM (October 2004). "Hereditary sensory neuropathies". Curr. Opin. Neurol. 17 (5): 569–77. doi:10.1097/00019052-200410000-00007. PMID 15367861. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=1350-7540&volume=17&issue=5&spage=569.
^ "eMedicine - Charcot-Marie-Tooth and Other Hereditary Motor and Sensory Neuropathies : Article by Aamir Hashmat". http://www.emedicine.com/neuro/TOPIC468.HTM.
^ Dyck PJ, Lambert EH (June 1968). "Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. I. Neurologic, genetic, and electrophysiologic findings in hereditary polyneuropathies". Arch. Neurol. 18 (6): 603–18. PMID 4297451.
^ Horacek, O.; Mazanec, R.; Morris, C. E.; Kobesova, A. (2007). "Spinal Deformities in Hereditary Motor and Sensory Neuropathy". Spine 32 (22): 2502–2508. doi:10.1097/BRS.0b013e3181573d4e. PMID 18090092. edit
^ Bertorini, T.; Narayanaswami, P.; Rashed, H. (2004). "Charcot-Marie-Tooth Disease (Hereditary Motor Sensory Neuropathies) and Hereditary Sensory and Autonomic Neuropathies". The Neurologist 10 (6): 327–337. doi:10.1097/01.nrl.0000145596.38640.27. PMID 15518599. edit

Reilly MM (October 2000). "Classification of the hereditary motor and sensory neuropathies". Curr. Opin. Neurol. 13 (5): 561–4. doi:10.1097/00019052-200010000-00009. PMID 11073363. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=1350-7540&volume=13&issue=5&spage=561.

Nervous system pathology, PNS, somatic (G50–G64, 350–357)

Nerve, nerve root, plexus

Cranial nerve
disease

V (Trigeminal neuralgia, Anesthesia dolorosa) · VII (Facial nerve paralysis, Bell's palsy, Melkersson–Rosenthal syndrome, Parry–Romberg syndrome, Central seven) · XI (Accessory nerve disorder)

Radiculopathy,
plexopathy

brachial plexus (Brachial plexus lesion, Thoracic outlet syndrome) · Phantom limb

Mono-
neuropathy

Upper limb	median nerve (Carpal tunnel syndrome, Ape hand deformity) ulnar nerve (Ulnar nerve entrapment, Froment's sign, Guyon's canal syndrome, Ulnar claw) radial nerve (Radial neuropathy, Wrist drop, Cheiralgia paresthetica) long thoracic nerve (Winged scapula)

Lower limb	lateral cutaneous nerve of thigh (Meralgia paraesthetica) tibial nerve (Tarsal tunnel syndrome) plantar nerve (Morton's neuroma) superior gluteal nerve (Trendelenburg's sign) sciatic nerve (Piriformis syndrome)

General	Causalgia · Mononeuritis multiplex · Neuropathy (Neuralgia/Neuritis) · Nerve compression syndrome

Polyneuropathies/Polyradiculoneuropathy

HMSN	Charcot–Marie–Tooth disease · Dejerine–Sottas disease · Refsum's disease · Hereditary spastic paraplegia

Autoimmune/demyelinating	Guillain–Barré syndrome · Chronic inflammatory demyelinating polyneuropathy

Other	Alcoholic polyneuropathy

M: PNS

anat(h/r/t/c/b/l/s/a)/phys(r)/devp/prot/nttr/nttm/ntrp

noco/auto/cong/tumr, sysi/epon, injr

proc, drug(N1B)

Hereditary motor and sensory neuropathy

Contents

Types

See also

References

Further reading