HMG20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related is a protein that in humans is encoded by the HMG20B gene.[1][2]
Interactions
HMG20B has been shown to interact with KIF4A,[3] HDAC1,[4] Histone deacetylase 2,[4][5] PHF21A,[4][6] RCOR1[4] and BRCA2.[4][7]
References
- ^ Sumoy L, Carim L, Escarceller M, Nadal M, Gratacos M, Pujana MA, Estivill X, Peral B (Jun 2000). "HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression". Cytogenet Cell Genet 88 (1–2): 62–7. doi:10.1159/000015486. PMID 10773667.
- ^ "Entrez Gene: HMG20B high-mobility group 20B". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10362.
- ^ Lee, Young Mi; Kim Wankee (Sep. 2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". Biochem. J. (England) 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMC 1223617. PMID 12809554. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1223617.
- ^ a b c d e Hakimi, Mohamed-Ali; Bochar Daniel A, Chenoweth Josh, Lane William S, Mandel Gail, Shiekhattar Ramin (May. 2002). "A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes". Proc. Natl. Acad. Sci. U.S.A. (United States) 99 (11): 7420–5. doi:10.1073/pnas.112008599. ISSN 0027-8424. PMC 124246. PMID 12032298. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=124246.
- ^ Hakimi, Mohamed-Ali; Dong Yuanshu, Lane William S, Speicher David W, Shiekhattar Ramin (Feb. 2003). "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes". J. Biol. Chem. (United States) 278 (9): 7234–9. doi:10.1074/jbc.M208992200. ISSN 0021-9258. PMID 12493763.
- ^ Iwase, Shigeki; Januma Aya, Miyamoto Kiyoko, Shono Naomi, Honda Arata, Yanagisawa Junn, Baba Tadashi (Sep. 2004). "Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression". Biochem. Biophys. Res. Commun. (United States) 322 (2): 601–8. doi:10.1016/j.bbrc.2004.07.163. ISSN 0006-291X. PMID 15325272.
- ^ Marmorstein, L Y; Kinev A V, Chan G K, Bochar D A, Beniya H, Epstein J A, Yen T J, Shiekhattar R (Jan. 2001). "A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression". Cell (United States) 104 (2): 247–57. doi:10.1016/S0092-8674(01)00209-4. ISSN 0092-8674. PMID 11207365.
Further reading
- Wattler F, Wattler S, Kelly M, et al. (1999). "Cloning, chromosomal location, and expression analysis of murine Smarce1-related, a new member of the high-mobility 365 group gene family". Genomics 60 (2): 172–8. doi:10.1006/geno.1999.5913. PMID 10486208.
- Marmorstein LY, Kinev AV, Chan GK, et al. (2001). "A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression". Cell 104 (2): 247–57. doi:10.1016/S0092-8674(01)00209-4. PMID 11207365.
- Lee YM, Shin H, Choi W, et al. (2002). "Characterization of human SMARCE1r high-mobility-group protein". Biochim. Biophys. Acta 1574 (3): 269–76. PMID 11997092.
- Hakimi MA, Bochar DA, Chenoweth J, et al. (2002). "A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes". Proc. Natl. Acad. Sci. U.S.A. 99 (11): 7420–5. doi:10.1073/pnas.112008599. PMC 124246. PMID 12032298. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=124246.
- Wang C, McCarty IM, Balazs L, et al. (2002). "Cloning a cDNA encoding an alternatively spliced protein of BRCA2-associated factor 35". Biochem. Biophys. Res. Commun. 295 (1): 129–35. doi:10.1016/S0006-291X(02)00624-1. PMID 12083779.
- Wang C, McCarty IM, Balazs L, et al. (2002). "Immunohistological detection of BRAF25 in human prostate tumor and cancer specimens". Biochem. Biophys. Res. Commun. 295 (1): 136–41. doi:10.1016/S0006-291X(02)00625-3. PMID 12083780.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Hakimi MA, Dong Y, Lane WS, et al. (2003). "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes". J. Biol. Chem. 278 (9): 7234–9. doi:10.1074/jbc.M208992200. PMID 12493763.
- Lee YM, Kim W (2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". Biochem. J. 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMC 1223617. PMID 12809554. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1223617.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
- Iwase S, Januma A, Miyamoto K, et al. (2004). "Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression". Biochem. Biophys. Res. Commun. 322 (2): 601–8. doi:10.1016/j.bbrc.2004.07.163. PMID 15325272.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
|
PDB gallery
|
|
|
|
2crj: Solution structure of the HMG domain of mouse HMG domain protein HMGX2
|
|
|
|