HLA-B63

HLA-B (alpha)-β2MG with bound peptide
major histocompatibility complex (human), class I, B63
Alleles *1516, *1517
Structure (See HLA-B)
Shared data
Locus chr.6 6p21.31

HLA-B63 (B63) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B.[1]

Further information: HLA-serotype tutorial

B63 is one of many split antigens of the broad antigen, B15. B63 identifies the B*1516 and B*1517 allele products.

Serotype

Serotypes B15, B62, B63, B70, B71, B72, B75, B76, B77 recognition of the
HLA B*15 gene products[2]
B*15 B15 B62 B63 B70 B71 B72 B75 B76 B77 Sample
allele  %  %  %  %  %  %  %  %  % size (N)
*1516 3 80 816
*1517 2 88 797
Alleles link-out to IMGT/HLA Databease at EBI


Alleles

HLA B*1516 frequencies
freq
ref. Population (%)
[3] Ivory Coast Akan Adiopodoume 4.6
Cameroon Bamileke 3.2
USA African Americans (3) 1.9
Italy South Campania 1.6
United Arab Emerates 1.5
Brazil 1.4
Azores S. Maria and S. Miguel 1.3
Zimbabwe Harare Shona 1.3
Cameroon Beti 1.1
Cameroon Yaounde 1.1
Mali Bandiagara 1.1
Tunisia Tunis 1.1
Kenya Nandi 1.0
Cape Verde SE Islands 0.8
Kenya 0.7
Uganda Kampala 0.6
Brazil Belo Horizonte 0.5
South Africian Natal Zulu 0.5
Sudanese 0.5
Tunisia 0.5
Kenya Luo 0.4
Oman 0.4


HLA B*1517 frequencies
freq
ref. Population (%)
[3] India Khandesh Pawra 9.0
South Africa Natal Tamil 3.1
Saudi Arabia Guraiat and Hail 2.7
Mexico Zaptotec Oaxaca 2.2
India North Hindus 1.9
Bulgaria 1.8
India North Delhi 1.6
China Inner Mongolia 1.5
Georgia Tibilisi Georgians 1.4
Kenya Luo 1.3
Cuban Mulatto 1.2
Brazil Belo Horizonte 1.1
Cameroon Yaounde 1.1
Portugal North 1.1
Tunisia Tunis 1.1
Kenya Nandi 1.0
Portugal Centre 1.0
China Qinghai Hui 0.9
Israel Ashk. and Non Ashk.i Jews 0.9
Azores Terceira Island 0.8
Cape Verde Southeastern Islands 0.8
France South East 0.8
India New Delhi 0.8
Russia Tuva pop 2 0.8
Sudanese 0.8
USA African Americans pop3 0.8
USA Caucasian pop2 0.8
Brazil 0.7
Cuban White 0.7
Thailand 0.7
USA Philadelphia Caucasians 0.7
Cameroon Beti 0.6
Romanian 0.6
Czech Republic 0.5
Singapore Thai 0.5
Spain Eastern Andalusia Gipsy 0.5

References

  1. ^ Marsh SG, Albert ED, Bodmer WF et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–369. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720. 
  2. ^ derived from IMGT/HLA
  3. ^ a b Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. 

HLA-B · B5 (B51 · B52) · B7 · B8 · B12 (B44 · B45) · B13 · B14 (B64 · B65) · B15 (B62 · B63 · B70 · B71 · B72 · B75 · B76 · B77) · B16 (B38 · B39) · B17 (B57 · B58) · B18 · B21 (B49 · B50) · B22 (B54 · B55 · B56) · B27 · B35 · B37 · B40 (B60 · B61) · B41 · B42 · B46 · B47 · B48 · B53 · B59 · B67 · B73 · B78 · B81 · B*82 · B*83