Glycidol

Glycidol[1]
Identifiers
CAS number 556-52-5 Y
PubChem 11164
ChemSpider 10691 Y
KEGG C10920 Y
ChEBI CHEBI:30966 Y
Jmol-3D images Image 1
Properties
Molecular formula C3H6O2
Molar mass 74.08 g mol−1
Density 1.1143 g/cm³
Melting point

−54 °C

Boiling point

61–62 °C, 151 °F

Hazards
MSDS External MSDS
NFPA 704
2
4
3
 Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Glycidol is an organic compound that contains both epoxide and alcohol functional groups. Being bifunctional, it has a variety of industrial uses. The compound is a slightly viscous liquid that is slightly unstable and is not often encountered in pure form.

Contents

Synthesis and applications

Glycidol is prepared by the epoxidation of allyl alcohol.[2]

Glycidol is used as a stabilizer for natural oils and vinyl polymers and as a demulsifier. It is used as a chemical intermediate in the synthesis of glycerol, glycidyl ethers, esters and amines. It is used in surface coatings, chemical synthesis, pharmaceuticals, sanitary chemicals and sterilizing milk of magnesia, and as a gelation agent in solid propellants.[3]

Safety

Glycidol is an irritant of the skin, eyes, mucous membranes, and upper respiratory tract. Exposure to glycidol may also cause central nervous system depression, followed by central nervous system stimulation.[4] It is listed as IARC group2 carcinogen.

See also

References

  1. ^ Merck Index, 11th Edition, 4385.
  2. ^ Guenter Sienel, Robert Rieth, Kenneth T. Rowbottom "Epoxides" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a09_531
  3. ^ Glycidol at chemicalland21.com
  4. ^ OSHA guidelines for glycidol