Globoside

A globoside is a type of glycosphingolipid with more than one sugars as the side chain (or R group). The sugars are usually a combination of N-Acetylgalactosamine, D-glucose or D-galactose. A glycosphingolipid that has only one sugar as the side chain is called a cerebroside.

The side chain can be cleaved by beta-hexosaminidase. If the enzyme is not functioning correctly, then globosides can accumulate, leading to Sandhoff disease.

External links

Globoside at eMedicine Dictionary
MeSH Globosides

Glycoconjugates, lipids and glycolipids: sphingolipids and glycosphingolipids, and metabolic intermediates

Ceramide

Cerebroside (Galactocerebroside, Glucocerebroside) · Lactosylceramide

Ganglioside
pathway

From ganglioside	GM1 · GM2 · GD2

From globoside	Globotriaosylceramide

From sphingomyelin	Glucocerebroside

From sulfatide	Galactocerebroside

To sphingosine	Ceramide

Other

Sphingosine-1-phosphate

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i