Gangliosidosis

Gangliosidosis
Classification and external resources
ICD-10	E 75.0-E 75.1
ICD-9	330.1
MeSH	D005733

Gangliosidosis is a lipid storage disorder caused by the accumulation of lipids known as gangliosides. There are two distinct genetic causes of the disease. Both are autosomal recessive and affect males and females equally.

Types

GM1 gangliosidoses - GM1
GM2 gangliosidoses - GM2

From ganglioside (gangliosidoses)	Ganglioside: GM1 gangliosidoses · GM2 gangliosidoses (Sandhoff disease, Tay-Sachs disease, AB variant)

From globoside	Globotriaosylceramide: Fabry's disease

From sphingomyelin	Sphingomyelin: phospholipid: Niemann–Pick disease (SMPD1-associated, type C) Glucocerebroside: Gaucher's disease

From sulfatide (sulfatidoses, leukodystrophy)	Sulfatide: Metachromatic leukodystrophy · Multiple sulfatase deficiency Galactocerebroside: Krabbe disease

To sphingosine	Ceramide: Farber disease

NCL

Infantile · Jansky-Bielschowsky disease · Batten disease

Other

Cerebrotendineous xanthomatosis · Cholesteryl ester storage disease (Lysosomal acid lipase deficiency/Wolman disease) · Sea-blue histiocyte syndrome

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

External links

Hide & Seek Foundation for Lysosomal Disease Research

Gangliosidosis

Types

See also

External links