GRIPAP1

GRIP1 associated protein 1
Identifiers
Symbols GRIPAP1; DKFZp434P0630; GRASP-1; KIAA1167; MGC126593; MGC126595
External IDs OMIM300408 MGI1859616 HomoloGene41348 GeneCards: GRIPAP1 Gene
Orthologs
Species Human Mouse
Entrez 56850 54645
Ensembl ENSG00000068400 ENSMUSG00000031153
UniProt Q4V328 Q8VD04
RefSeq (mRNA) NM_020137.3 NM_207670.1
RefSeq (protein) NP_064522.3 NP_997553.1
Location (UCSC) Chr X:
48.83 – 48.86 Mb
Chr X:
7.37 – 7.4 Mb
PubMed search [1] [2]

GRIP1-associated protein 1 is a protein that in humans is encoded by the GRIPAP1 gene.[1][2]

GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated with the GRIP/AMPA receptor complex in brain (Ye et al., 2000).[supplied by OMIM][2]

Interactions

GRIPAP1 has been shown to interact with GRIP1.[1]

References

  1. ^ a b Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (Aug 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157. 
  2. ^ a b "Entrez Gene: GRIPAP1 GRIP1 associated protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56850. 

Further reading