G3BP2

GTPase activating protein (SH3 domain) binding protein 2
Identifiers
Symbols G3BP2;
External IDs MGI2442040 HomoloGene40792 GeneCards: G3BP2 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 9908 23881
Ensembl ENSG00000138757 ENSMUSG00000029405
UniProt Q9UN86 Q3TEL4
RefSeq (mRNA) NM_012297.4 NM_001080794
RefSeq (protein) NP_036429.2 NP_001074263
Location (UCSC) Chr 4:
76.57 – 76.65 Mb
Chr 5:
92.48 – 92.51 Mb
PubMed search [1] [2]

Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene.[1][2][3]

Interactions

G3BP2 has been shown to interact with IκBα.[4]

References

  1. ^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811. 
  2. ^ Kennedy D, Wood SA, Ramsdale T, Tam PP, Steiner KA, Mattick JS (Jun 1998). "Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif". Biomed Pept Proteins Nucleic Acids 2 (3): 93–9. PMID 9575347. 
  3. ^ "Entrez Gene: G3BP2 GTPase activating protein (SH3 domain) binding protein 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9908. 
  4. ^ Prigent, M; Barlat I, Langen H, Dargemont C (Nov. 2000). "IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2". J. Biol. Chem. (UNITED STATES) 275 (46): 36441–9. doi:10.1074/jbc.M004751200. ISSN 0021-9258. PMID 10969074. 

Further reading