Formononetin

Formononetin
Identifiers
CAS number 485-72-3 Y
PubChem 5280378
ChemSpider 4444070 Y
KEGG C00858 Y
ChEBI CHEBI:18088 Y
ChEMBL CHEMBL242341 Y
Beilstein Reference 237979
Jmol-3D images Image 1
Properties
Molecular formula C16H12O4
Molar mass 268.26 g/mol
Exact mass 268.073559
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Formononetin is an O-methylated isoflavone. It is found in a number of plants and herbs like the red clover.[1] Along with other phytoestrogens, it predominantly occurs in leguminous plants and Fabaceae, particularly in beans, such as green beans, lima beans, soy and many others, as the free aglycone or in form of its glucoside ononin.[2]

Metabolism

The enzyme 4'-methoxyisoflavone 2'-hydroxylase uses formononetin, NADPH, H+, and O2 to produce 2'-hydroxyformononetin, NADP+ and H2O.

The enzyme Isoflavone 3'-hydroxylase uses formononetin, NADPH, H+, and O2 to produce calycosin (3'-hydroxyformononetin), NADP+ and H2O.

Glycosides

Ononin is the 7-O-glucoside of formononetin.

References