| Systematic (IUPAC) name | |
|---|---|
| (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | C |
| Legal status | ? |
| Routes | Topical |
| Pharmacokinetic data | |
| Metabolism | Hepatic, CYP3A4-mediated |
| Half-life | 1.3 to 1.7 hours |
| Identifiers | |
| CAS number | 67-73-2 |
| ATC code | C05AA10 D07AC04 S01BA15 S02BA08 |
| PubChem | CID 6215 |
| DrugBank | APRD00977 |
| ChemSpider | 5980 |
| UNII | 0CD5FD6S2M |
| KEGG | D01825 |
| ChEMBL | CHEMBL989 |
| Chemical data | |
| Formula | C24H30F2O6 |
| Mol. mass | 452.488 g/mol |
| SMILES | eMolecules & PubChem |
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Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. A typical dosage strength used in dermatology is 0.01–0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin.
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