FinP

FinP
Predicted secondary structure and sequence conservation of FinP
Identifiers
Symbol FinP
Rfam RF00107
Other data
RNA type Gene
Domain(s) Bacteria
SO 0000644

FinP encodes an antisense non-coding RNA gene that is complementary to part of the TraJ 5' UTR. The FinOP system regulates the transfer of F-like plasmids. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.[1][2]

References

  1. ^ Jerome, LJ; van Biesen T, Frost LS (1999). "Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E". J Mol Biol 285 (4): 1457–1473. doi:10.1006/jmbi.1998.2404. PMID 9917389. 
  2. ^ Arthur, DC; Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN (2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". EMBO J 22 (23): 6346–6355. doi:10.1093/emboj/cdg607. PMC 291848. PMID 14633993. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=291848. 

External links