Ferruginol | |
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(4bS,8aS)-4b,8,8-Trimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol |
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Identifiers | |
CAS number | 514-62-5 |
PubChem | 442027 |
ChemSpider | 390582 |
ChEMBL | CHEMBL197308 |
Jmol-3D images | Image 1 |
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Properties | |
Molecular formula | C20H30O |
Molar mass | 286.45 g/mol |
Exact mass | 286.229666 u |
(verify) (what is: / ?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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Infobox references |
Ferruginol is a natural phenol and a meroterpene (a chemical compound containing a terpenoid substructure) that has been isolated from the needles of the redwood Sequoia sempervirens. The terpenoid part is a diterpene of the abietane chemical class.
Research published in 2005 found that this and other compound of the class from Sequoia have anti-tumor properties, and showed in vitro human colon, breast, and lung tumor reduction and reduction in oncogene transformed cells as well. Specific activity of tumor growth inhibition (GI) is 2-5 micrograms/milliliter.[1]
Ferruginol has also been found to have antibacterial activity.[2][3] Gastroprotective effects of ferruginol have also been noted.[4]