| Systematic (IUPAC) name | |
|---|---|
| 1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)phenyl]methoxy}ethyl]-1H-imidazole | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | prescription |
| Routes | ovule, spray, cream |
| Identifiers | |
| CAS number | 72479-26-6 |
| ATC code | D01AC12 G01AF12 |
| PubChem | CID 51755 |
| UNII | QG05NRB077 |
| KEGG | D02582 |
| Chemical data | |
| Formula | C24H20Cl2N2OS |
| Mol. mass | 455.4 g/mol |
| (what is this?) (verify) |
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Fenticonazole is an azole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis.
Antimicrobial Action Fenticonazole is an imidazole antifungal active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.
Uses and Administration A 200-mg pessary is inserted into the vagina at bedtime for 3 nights or a 600-mg pessary is inserted once only at bedtime. Fenticonazole nitrate is also applied topically as a 2% cream or solution for the treatment of fungal skin infections.
Adverse Effects and Precautions Burning and itching have been reported after the application of fenticonazole nitrate.
Intravaginal preparations of fenticonazole may damage latex contraceptives and additional contraceptive measures are therefore necessary during local administration.
For a discussion of the caution needed when using azole antifungals during pregnancy, see under Pregnancy in Precautions of Fluconazole, .
Preparations Single-ingredient Preparations The symbol ¤ denotes a preparation which is discontinued or no longer actively marketed.
Argentina: Lomexin¤; Austria: Fenizolan¤; Lomexin; Brazil: Fentizol; Lomexin; Czech Republic: Lomexin; France: Lomexin; Terlomexin; Germany: Fenizolan; Lomexin; Greece: Lomexin; Hungary: Gynoxin; Italy: Falvin; Fentiderm¤; Fentigyn¤; Lomexin; Mexico: Lomexin; South Africa: Lomexin; Singapore: Lomexin¤; Spain: Laurimic; Lomexin; Micofulvin¤; Switzerland: Mycodermil; United Kingdom: Lomexin¤; Venezuela: Mycofentin;
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