FCRL1

Fc receptor-like 1

Identifiers

FCRL1; DKFZp667O1421; FCRH1; IFGP1; IRTA5

External IDs

OMIM: 606508 MGI: 2442862 HomoloGene: 50472 GeneCards: FCRL1 Gene

Gene Ontology
Molecular function	• receptor activity
Cellular component	• plasma membrane • integral to membrane
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

ENSG00000163534

ENSMUSG00000059994

n/a

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 1:
157.76 – 157.79 Mb

Chr 3:
87.18 – 87.2 Mb

PubMed search

Fc receptor-like protein 1 is a protein that in humans is encoded by the FCRL1 gene.^[1]^[2]^[3]

References

^ Davis RS, Wang YH, Kubagawa H, Cooper MD (Aug 2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc Natl Acad Sci U S A 98 (17): 9772–9777. doi:10.1073/pnas.171308498. PMC 55528. PMID 11493702. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=55528.
^ Miller I, Hatzivassiliou G, Cattoretti G, Mendelsohn C, Dalla-Favera R (Apr 2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood 99 (8): 2662–2669. doi:10.1182/blood.V99.8.2662. PMID 11929751.
^ "Entrez Gene: FCRL1 Fc receptor-like 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115350.

Further reading

Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL". Immunogenetics 59 (4): 323–328. doi:10.1007/s00251-007-0195-9. PMID 17273841.
Leu CM, Davis RS, Gartland LA et al. (2005). "FcRH1: an activation coreceptor on human B cells". Blood 105 (3): 1121–1126. doi:10.1182/blood-2004-06-2344. PMID 15479727.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Guselnikov SV, Ershova SA, Mechetina LV et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1". Immunogenetics 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID 12037601.