Etoxeridine

Etoxeridine

Systematic (IUPAC) name
ethyl 1-[2-(2-hydroxyethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
Clinical data
Pregnancy cat.	?
Legal status	? (UK) Schedule I (US)
Identifiers
CAS number	469-82-9^Y
ATC code	None
PubChem	CID 61122
DrugBank	DB01505
ChemSpider	55070^Y
UNII	RHW35E1G7E^Y
Synonyms	Etoxeridine, Carbetidine, Atenos
Chemical data
Formula	C₁₈H₂₇N O₄
Mol. mass	321.41 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C18H27NO4/c1-2-23-17(21)18(16-6-4-3-5-7-16)8-10-19(11-9-18)12-14-22-15-13-20/h3-7,20H,2,8-15H2,1H3^Y Key:KJTKYGFGPQSRRA-UHFFFAOYSA-N^Y
Y(what is this?) (verify)

Etoxeridine (Carbetidine, Atenos) is a 4-phenyl piperidine derivative that is related to the opioid analgesic drug pethidine (meperidine).

Etoxeridine was developed in the 1950s^[1] and investigated for use in surgical anesthesia, however it was never commercialised and is not currently used in medicine.^[2]^[3]^[4]

References

^ BE Patent 558883
^ Merlevede E, Levis S. Pharmacological study of carbetidine, a new synthetic analgesic. (French). Archives Internationales de Pharmacodynamie et de Therapie. 1958 May 1;115(1-2):213-32.
^ Sironi PG. Brief note on a new synthetic analgesic: carbetidine hydrochloride. (Italian). Minerva Anestesiologica. 1959 Jun;25(6):251-4.
^ Crawford JS, Foldes FF. Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia. British Journal of Anaesthesia. 1959 Aug;31:348-51.