Ethylenediamine dihydroiodide

Ethylenediamine dihydroiodide

IUPAC name Ethane-1,2-diamine dihydroiodide
Other names Ethylenediammonium diiodide Jodethamine Hydrodine
Identifiers
Abbreviations	EDDI
CAS number	5700-49-2
PubChem	21921
ChemSpider	20604^Y
Jmol-3D images	Image 1 Image 2
SMILES NCCN.I.I I.I.NCCN
InChI InChI=1S/C2H8N2.2HI/c3-1-2-4;;/h1-4H2;21H^Y Key: IWNWLPUNKAYUAW-UHFFFAOYSA-N^Y InChI=1/C2H8N2.2HI/c3-1-2-4;;/h1-4H2;21H Key: IWNWLPUNKAYUAW-UHFFFAOYAJ
Properties
Molecular formula	C₂H₁₀I₂N₂
Molar mass	315.92 g/mol
Appearance	Colorless to light yellow crystalline powder
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Ethylenediamine dihydroiodide (EDDI) is a water-soluble salt of ethylenediamine and hydrogen iodide. It is a colorless to light yellow crystalline powder. Its chemical formula is C₂H₆N₂.2HI. It is nonflammable, but iodine may be released during a fire.

EDDI is used as a pet food additive and cattle feed additive with high bioavailability. It is used to prevent iodine deficiency. The United States Food and Drug Administration suggests a limit of intake to 50 mg/head/day.^[1] Although EDDI is generally recognized as safe (GRAS) only as a nutrient source of iodine, administration of EDDI also has preventative effects on foot rot in cattle.^[2]

EDDI may react with sulfates and release free iodine. Other iodine supplements in animal feed are calcium iodate (most stable) and potassium iodide (most water-soluble, least stable).

References

^ The Elimination of Iodine Deficiency Disorders, A Resource Package for Central and Eastern Europe, the Commonwealth of Independent States and Baltic States
^ Berg JN, Maas JP, Paterson JA, Krause GF, Davis LE (1984). "Efficacy of ethylenediamine dihydriodide as an agent to prevent experimentally induced bovine foot rot". Am. J. Vet. Res. 45 (6): 1073–8. PMID 6146277.