Ergovaline

Ergovaline
Clinical data
Pregnancy cat.  ?(US)
Legal status  ?
Identifiers
CAS number 2873-38-3
ATC code  ?
PubChem CID 104843
Chemical data
Formula C29H35N5O5 
Mol. mass 533.619 g/mol
 Y(what is this?)  (verify)

Ergovaline is an ergopeptine and one of the ergot alkaloids. It is usually found in endophyte-infected species of grass like Tall fescue[1] or Perennial Ryegrass.[2] It is toxic to cattle feeding on infected grass, probably because is acts as a vasoconstrictor.[1][3]

References

  1. ^ a b Richard Browning (2003). Tall Fescue Endophyte Toxicosis in Beef Cattle: Clinical Mode of Action and Potential Mitigation through Cattle Genetics. Beef Improvement Federation. http://www.bifconference.com/bif2003/BIFsymposium_pdfs/Browning.pdf. 
  2. ^ Hovermale, J. T.; Craig, A. M. (2001). "Correlation of Ergovaline and Lolitrem B Levels in Endophyte-Infected Perennial Ryegrass (Lolium Perenne)". Journal of Veterinary Diagnostic Investigation 13 (4): 323–327. doi:10.1177/104063870101300407. PMID 11478604.  edit
  3. ^ Schnitzius, J. M.; Hill, N. S.; Thompson, C. S.; Craig, A. M. (2001). "Semiquantitative determination of ergot alkaloids in seed, straw, and digesta samples using a competitive enzyme-linked immunosorbent assay". Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 13 (3): 230–237. PMID 11482600.  edit