Epalrestat

Epalrestat
IUPAC name

2-[(5Z)-5-[(E)-3-phenil-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid
Identifiers
CAS number 82159-09-9 Y
PubChem 1549120
KEGG D01688 Y
ChEMBL CHEMBL56337 N
Jmol-3D images Image 1
Properties
Molecular formula C15H13NO3S2
Molar mass 319.401 g/mol
 N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Epalrestat is an aldose reductase inhibitor.

"Long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, particularly in subjects with good glycemic control and limited microangiopathy." [1]

Brand name

1. Eparel 50(Microlabs Ltd),India 2. Aldonil (Zydus Medica), India

References

  1. ^ http://www.medscape.com/viewarticle/540494 July 2006 Epalrestat May Delay Progression and Reduce Symptoms of Diabetic Neuropathy

External links