Edobacomab
Edobacomab, codenamed E5, is a mouse monoclonal antibody that was investigated as a possible treatment for sepsis caused by Gram-negative bacterial infections.
Further reading
- Greenman RL, Schein RM, Martin MA et al. (August 1991). "A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group". JAMA 266 (8): 1097–102. doi:10.1001/jama.266.8.1097. PMID 1865542.
- Bone RC, Balk RA, Fein AM et al. (June 1995). "A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group". Crit. Care Med. 23 (6): 994–1006. PMID 7774238. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0090-3493&volume=23&issue=6&spage=994.
- Angus DC, Birmingham MC, Balk RA et al. (April 2000). "E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators". JAMA 283 (13): 1723–30. doi:10.1001/jama.283.13.1723. PMID 10755499. http://jama.ama-assn.org/cgi/pmidlookup?view=long&pmid=10755499.
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| Viral ("-vi(r)-") |
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| Bacterial ("-ba(c)-") |
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Human ("-bacu-")
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Mouse ("-baco-")
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Edobacomab
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Humanized ("-bazu-")
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| Toxin ("-tox(a)-") |
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