ESC

ESC may refer to:

As an abbreviation

• Ecole Supérieure de Commerce, a business school in the French system of "Grandes Ecoles"
• Edison State College
• Edmonton Ski Club
• Electronic stability control
• Electronic Systems Center
• Electronic speed control
• Embedded Systems Conference
• Embryonic stem cell
• Empire State College
• Empire Supporters Club
• English Subject Centre
• Environmental Stress Cracking, one of the most common causes of unexpected brittle failure of thermoplastic polymers
• Equitable Stroke Control, a feature of golf handicapping
• Escanaba, Michigan, the International Air Transport Association code for Delta County Airport
• Essential Services Commission
• Essex Senior Cup, a football competition in Essex, England
• Eurobodalla Shire Council
• European Shooting Confederation
• European Social Charter
• European Society of Cardiology
• European Students Conference, the largest biomedical scientific conference in Europe entirely run by students
• Eurovision Song Contest
• Sustainment Command (Expeditionary)
• European Space Camp
• European Super Cup
• Extended static checking

As a shortened version of the word escape

• Esc key on a keyboard
• Escape character in the C0 control code set

Others

• A son of the 5th century king Hengest, see Oisc of Kent