EMX1

Empty spiracles homeobox 1

Identifiers

External IDs

OMIM: 600034 MGI: 95387 HomoloGene: 55799 GeneCards: EMX1 Gene

Gene Ontology
Molecular function	• DNA binding • sequence-specific DNA binding transcription factor activity • sequence-specific DNA binding
Cellular component	• nucleus
Biological process	• multicellular organismal development • brain development • post-embryonic development • cerebral cortex regionalization • neuron differentiation • response to drug
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000135638

ENSMUSG00000033726

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 2:
73.14 – 73.16 Mb

Chr 6:
85.14 – 85.15 Mb

PubMed search

Homeobox protein EMX1 is a protein that in humans is encoded by the EMX1 gene.^[1]^[2]

References

^ Kastury K, Druck T, Huebner K, Barletta C, Acampora D, Simeone A, Faiella A, Boncinelli E (Dec 1994). "Chromosome locations of human EMX and OTX genes". Genomics 22 (1): 41–5. doi:10.1006/geno.1994.1343. PMID 7959790.
^ "Entrez Gene: EMX1 empty spiracles homeobox 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2016.

Further reading

Simeone A, Gulisano M, Acampora D, et al. (1992). "Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex.". EMBO J. 11 (7): 2541–50. PMC 556729. PMID 1352754. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=556729.
Solaro P, Greger B, Kemper B (1995). "Detection and partial purification of a cruciform-resolving activity (X-solvase) from nuclear extracts of mouse B-cells.". Eur. J. Biochem. 230 (3): 926–933. doi:10.1111/j.1432-1033.1995.tb20638.x. PMID 7601155.
Briata P, Di Blas E, Gulisano M, et al. (1997). "EMX1 homeoprotein is expressed in cell nuclei of the developing cerebral cortex and in the axons of the olfactory sensory neurons.". Mech. Dev. 57 (2): 169–80. doi:10.1016/0925-4773(96)00544-8. PMID 8843394.
Santi E, Capone S, Mennuni C, et al. (2000). "Bacteriophage lambda display of complex cDNA libraries: a new approach to functional genomics.". J. Mol. Biol. 296 (2): 497–508. doi:10.1006/jmbi.1999.3471. PMID 10669604.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.