EMID2

EMI domain containing 2

Identifiers

EMID2; COL26A1; EMI6; EMU2; MGC129848; SH2B

External IDs

OMIM: 608927 MGI: 2155345 HomoloGene: 11552 GeneCards: EMID2 Gene

Gene Ontology
Molecular function	• protein binding
Cellular component	• extracellular region • collagen
Biological process	• phosphate transport
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 7:
101.01 – 101.2 Mb

Chr 5:
137.22 – 137.36 Mb

PubMed search

[1]

[2]

Collagen alpha-1(XXVI) chain is a protein that in humans is encoded by the EMID2 gene.^[1]^[2]

References

^ Leimeister C, Steidl C, Schumacher N, Erhard S, Gessler M (Sep 2002). "Developmental expression and biochemical characterization of Emu family members". Dev Biol 249 (2): 204–18. doi:10.1006/dbio.2002.0764. PMID 12221002.
^ "Entrez Gene: EMID2 EMI domain containing 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=136227.

Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Sato K, Yomogida K, Wada T, et al. (2002). "Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary.". J. Biol. Chem. 277 (40): 37678–84. doi:10.1074/jbc.M205347200. PMID 12145293.
Velling T, Kusche-Gullberg M, Sejersen T, Gullberg D (1999). "cDNA cloning and chromosomal localization of human alpha(11) integrin. A collagen-binding, I domain-containing, beta(1)-associated integrin alpha-chain present in muscle tissues.". J. Biol. Chem. 274 (36): 25735–42. doi:10.1074/jbc.274.36.25735. PMID 10464311.
Rada JA, Cornuet PK, Hassell JR (1996). "Regulation of corneal collagen fibrillogenesis in vitro by corneal proteoglycan (lumican and decorin) core proteins.". Exp. Eye Res. 56 (6): 635–48. doi:10.1006/exer.1993.1081. PMID 8595806.
Homma N, Gejyo F, Isemura M, Arakawa M (1989). "Collagen-binding affinity of beta-2-microglobulin, a preprotein of hemodialysis-associated amyloidosis.". Nephron 53 (1): 37–40. doi:10.1159/000185699. PMID 2674742.

Protein: scleroproteins

Extracellular matrix

Collagen

Fibril forming	type I (COL1A1, COL1A2) · type II (COL2A1) · type III · type V (COL5A1, COL5A2, COL5A3) · COL24A1 · COL26A1

Other	FACIT: type IX (COL9A1, COL9A2, COL9A3) · type XII (COL12A1) · COL14A1 · COL16A1 · COL19A1 · COL20A1 · COL21A1 · COL22A1 basement membrane: type IV (COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6) multiplexin: COL15A1 · type XVIII (COL18A1, Endostatin) transmembrane: COL13A1 · COL17A1 · COL23A1 · COL25A1 other: type VI (COL6A1, COL6A2, COL6A3) · type VII (COL7A1) · type VIII (COL8A1, COL8A2) · type X (COL10A1) · type XI (COL11A1, COL11A2) · COL27A1 · COL28A1 · COL29A1

Enzymes	Prolyl hydroxylase/Lysyl hydroxylase · Cartilage associated protein/Leprecan · ADAMTS2 · Procollagen peptidase · Lysyl oxidase

Tenascin

Tenascin C · Tenascin X

Laminin

alpha (LAMA1, LAMA2, LAMA3, LAMA4, LAMA5) · beta (LAMB1, LAMB2, LAMB3, LAMB4) · gamma (LAMC1, LAMC2, LAMC3)

Other

ALCAM · Elastin (Tropoelastin) · Vitronectin · FRAS1 · FREM2 · Decorin · FAM20C · ECM1 · Matrix gla protein · Tectorin (TECTA, TECTB)

Other

Keratin/Cytokeratin · Gelatin · Reticulin · Cartilage oligomeric matrix protein

see also diseases
B proteins: BY STRUCTURE: membrane, globular (en, ca, an), fibrous

EMID2

References

Further reading