| early endosome antigen 1 | |
|---|---|
| Identifiers | |
| Symbol | EEA1 |
| Entrez | 8411 |
| HUGO | 3185 |
| OMIM | 605070 |
| RefSeq | NM_003566 |
| UniProt | Q15075 |
| Other data | |
| Locus | Chr. 12 q22 |
EEA1 is Early Endosome Antigen 1 protein that binds phospholipid vesicles containing phosphatidylinositol 3-phosphate, which is necessary for endosomal trafficking. It binds lipids through its FYVE domain and forms a homodimer through a coiled coil domain.