Fast Green FCF

Fast Green FCF
Identifiers
CAS number 2353-45-9 Y
PubChem 16888
ChemSpider 16002 Y
UNII 3P3ONR6O1S Y
KEGG C19423 N
Jmol-3D images Image 1
Properties
Molecular formula C37H37N2O10S3+
Molar mass 765.89 g/mol
Hazards
R-phrases R36 R37 R38
 N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Fast Green FCF, also called Food green 3, FD&C Green No. 3, Green 1724, Solid Green FCF, and C.I. 42053, is a sea green triarylmethane food dye. Its E number is E143.

Fast Green FCF is recommended as a replacement of Light Green SF yellowish in Masson's trichrome, as its color is more brilliant and less likely to fade. It is used as a quantitative stain for histones at alkaline pH after acid extraction of DNA. It is also used as a protein stain in electrophoresis. Its absorption maximum is at 625 nm.

Fast Green FCF is poorly absorbed by the intestines. [1] Its use as a food dye is prohibited in European Union and some other countries. It can be used for tinned green peas and other vegetables, jellies, sauces, fish, desserts, and dry bakery mixes at level of up to 100 mg/kg. [2] In the United States, Fast Green FCF is the least used of the seven main FDA approved dyes.

Toxicology

This substance has been found to have tumorigenic effects in experimental animals, as well as mutagenic effects in both experimental animals and humans. It furthermore risks irritation of eyes, skin, digestive tract, and respiratory tract in its undiluted form.[3]

Notes