Dihydropyridine

Dihydropyridine
Identifiers
CAS number 3337-17-5 Y
PubChem 104822
ChemSpider 94619 Y
MeSH 1,4-dihydropyridine
Jmol-3D images Image 1
Properties
Molecular formula C5H7N
Molar mass 81.1158 g mol-1
Exact mass 81.057849229 g mol-1
 Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dihydropyridine is a molecule based upon pyridine, and the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond. They are particularly well known in pharmacology as L-type calcium channel blockers.

Contents

Class members

The L-type calcium channel blockers include, in alphabetical order (brand names vary in different countries):

Name Image Brand name Discovered
Amlodipine Norvasc, Istin
Aranidipine
Azelnidipine
Barnidipine
Benidipine
Cilnidipine
Clevidipine
Cronidipine
Darodipine
Dexniguldipine
Efonidipine
Elnadipine
Elgodipine
Felodipine
Flordipine
Furnidipine
Iganidipine
Isradipine
Lacidipine
Lemildipine
Lercanidipine Zanidip
Manidipine
Mesuldipine
Nicardipine Cardene
Nifedipine Adalat, Nifedical, Procardia
Niguldipine
Nimodipine Nimotop
Niludipine
Nilvadipine
Nisoldipine Sular
Nitrendipine
Olradipine
Oxodipine
Palonidipine
Pranidipine
Sagandipine
Sornidipine
Teludipine
Tiamdipine
Trombodipine
Watanidipine

See also

References

  1. ^ "1,4-dihydropyridine - Compound Summary". Pubchem Compound. USA: National Center for Biotechnology Information. 27 March 2005. Identification and Related Records. http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=104822&loc=ec_rcs. Retrieved 1 November 2011. 

External links