Dihydrofolic acid | |
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N-(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid |
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Other names
H2folate, DH |
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Identifiers | |
CAS number | 4033-27-6 |
PubChem | 98792 |
ChemSpider | 89228 |
MeSH | dihydrofolate |
ChEBI | CHEBI:15633 |
ChEMBL | CHEMBL46294 |
Jmol-3D images | Image 1 |
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Properties | |
Molecular formula | C19H21N7O6 |
Molar mass | 443.414 g/mol |
(verify) (what is: / ?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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Infobox references |
Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. Since tetrahydrofolate is needed to make both purines and pyrimidines, dihydrofolate reductase is targeted by various drugs to prevent nucleic acid synthesis. Dihydrofolic acid is also known by the name dihydrofolate - more commonly vitamin B9.
Click on genes, proteins and metabolites below to link to respective Wikipedia articles. [1]
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