Diflorasone

Diflorasone
Systematic (IUPAC) name
[17-(2-Acetyloxyacetyl)- 6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16- octahydrocyclopenta[a]phenanthren-17-yl] acetate
Clinical data
Trade names Psorcon
AHFS/Drugs.com monograph
MedlinePlus a602019
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 1-13-8 N
ATC code D07AC10
PubChem CID 71414
DrugBank APRD00921
ChemSpider 64504 Y
UNII T2DHJ9645W Y
KEGG D01327 Y
ChEBI CHEBI:31483 Y
ChEMBL CHEMBL1201380 N
Chemical data
Formula C26H32F2O7 
Mol. mass 494.525 g/mol
 N(what is this?)  (verify)

Diflorasone is a corticosteroid that comes in the form of a cream containing diflorasone diacetate. In is manufactured by E. Fougera & Co. and is used for its anti-inflammatory and anti-itching qualities, like other topical corticosteroids. It is often prescribed for psoriasis and atopic dermatitis, and also for Hailey–Hailey disease. It is considered to be of greater potency compared to other topical corticosteroids.

No long-term animal studies have been done to determine whether diflorasone could have carcinogenic properties.

Women who are breastfeeding their newborns should probably not use diflorasone since corticosteroids have been known to appear in breast milk and cause negative effects in a newborn, such as inhibited growth, but little data is available regarding whether topical corticosteroids like diflorasone would be present in great enough quantities to cause harm to an infant.