| Systematic (IUPAC) name | |
|---|---|
| 1,8-dihydroxyanthracene-9,10-dione | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Routes | Oral, rectal (enema) |
| Identifiers | |
| CAS number | 117-10-2 |
| ATC code | A06AB03 A06AB53 A06AG03 |
| PubChem | CID 2950 |
| DrugBank | DB04816 |
| ChemSpider | 2845 |
| UNII | Z4XE6IBF3V |
| KEGG | D07107 |
| ChEBI | CHEBI:3682 |
| ChEMBL | CHEMBL53418 |
| Chemical data | |
| Formula | C14H8O4 |
| Mol. mass | 240.211 g/mol |
| SMILES | eMolecules & PubChem |
|
|
| (what is this?) (verify) |
|
1,8-Dihydroxyanthraquinone is an organic substance with formula C14H8O4, formally derived from anthraquinone by the replacement of two hydrogen atoms by hydroxyl groups (OH). It is used in some countries as a stimulant laxative, under the generic names dantron or chrysazin.
It should not be confused with ondansetron, an unrelated drug that was marketed in South Africa uder the trade name "Dantron".
In the USA, dantron is not used because it is considered to be a carcinogen.[1]
In the UK it is considered a possible carcinogen and so its licence is restricted to patients who already have a diagnosis of terminal cancer (i.e. it is mainly used in palliative care to counteract the constipating effects of opioids) Its British Approved Name was Danthron, but it has now been changed to "dantron", the recommended International Nonproprietary Name.[2]
Dantron has the notable side-effect of causing red-coloured urine.
|
||||||||||||||||||||||||||||