Thymidine triphosphate

Thymidine triphosphate

IUPAC name [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
Other names dTTP, 2'-deoxythymidine triphosphate
Identifiers
CAS number	365-08-2^N=
PubChem	64968
ChemSpider	58493^N=
MeSH	thymidine+5'-triphosphate
ChEMBL	CHEMBL363559^N
Jmol-3D images	Image 1
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
Properties
Molecular formula	C₁₀H₁₇N₂O₁₄P₃
Molar mass	482.168
N Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Thymidine triphosphate (dTTP) is one of the five nucleoside triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleotide triphosphates, thymidine triphosphate does not contain the "deoxy" prefix in its name.^[1] The corresponding ribonucleoside triphosphate is called 5-methyluridine triphosphate.

It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.

Reflist

^ Coghill, Anne M.; Garson, Lorrin R., ed (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 9780841239999.

Nucleic acid constituents

Ribonucleoside	Adenosine · Guanosine · 5-Methyluridine · Uridine · Cytidine

Deoxyribonucleoside	Deoxyadenosine · Deoxyguanosine · Thymidine · Deoxyuridine · Deoxycytidine

Nucleotide
(Nucleoside monophosphate)

Nucleoside diphosphate

biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i