DPI-287

DPI-287
Systematic (IUPAC) name
4-[(R)-[(2S,5R)-2,5-dimethyl-4-benzylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N,N-diethylbenzamide
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
ATC code  ?
PubChem CID 21025820
Chemical data
Formula C31H39N3O2 
Mol. mass 485.659 g/mol
SMILES eMolecules & PubChem
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DPI-287 is a drug that is used in scientific research. It is a highly selective agonist for the δ-opioid receptor, which produces less convulsions than most drugs from this family.[1] It has antidepressant effects.[2]

References

  1. ^ Jutkiewicz, EM (2006). "The antidepressant -like effects of delta-opioid receptor agonists". Molecular interventions 6 (3): 162–9. doi:10.1124/mi.6.3.7. PMID 16809477. 
  2. ^ Jutkiewicz EM, Chang KJ, Rice KC, Woods JH. (2005) Characterization of a novel nonpeptide delta-opioid agonist analog DPI287 with antidepressant-like activity. Experimental Biology meeting abstracts. FASEB J. 19, Abstract # 874.4