| Dachsous 1 (Drosophila) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | DCHS1; CDH25; CDHR6; FIB1; FLJ11790; KIAA1773; PCDH16 | ||||||||||||
| External IDs | OMIM: 603057 MGI: 2685011 HomoloGene: 2771 GeneCards: DCHS1 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 8642 | 233651 | |||||||||||
| Ensembl | ENSG00000166341 | ENSMUSG00000036862 | |||||||||||
| UniProt | Q96JQ0 | Q6PAS4 | |||||||||||
| RefSeq (mRNA) | NM_003737 | NM_001162943.1 | |||||||||||
| RefSeq (protein) | NP_003728 | NP_001156415.1 | |||||||||||
| Location (UCSC) | Chr 11: 6.64 – 6.68 Mb |
Chr 7: 112.9 – 112.94 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Protein dachsous homolog 1, also known as protocadherin-16 (PCDH16) or cadherin-19 (CDH19) or cadherin-25 (CDH25) or fibroblast cadherin-1 (FIB1), is a protein that in humans is encoded by the DCHS1 gene.[1][2]
This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing.[1]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.