Cilofungin

Cilofungin
IUPAC name

N-[(11R,20R,21R,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,21,25-tetrahydroxy-3,15-bis(1-hydroxyethyl)-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.09,13]heptacosan-18-yl]-4-(octyloxy)benzamide
Identifiers
CAS number 79404-91-4
PubChem 71762
UNII 8ZJC54A39X Y
MeSH Cilofungin
Properties
Molecular formula C49H71N7O17
Molar mass 1030.12 g mol−1
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Cilofungin is the first clinically applied member of the Echinocandin family of antifungal drug. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the conversion of lanosterol to ergosterol).[1]

References

  1. ^ Hudler, George (1998). Magical Mushrooms, Mischievous Molds. Princeton, New Jersey: Princeton University Press. pp. 112. ISBN 978-0-691-07016-2.