Clinical data | |
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Pregnancy cat. | ? |
Legal status | ℞ Prescription only |
Routes | Injection into intervertebral disc |
Identifiers | |
ATC code | M09AB01 |
UNII | 1UK146T40N |
ChEMBL | CHEMBL1201626 |
Chemical data | |
Formula | ? |
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Chymopapain (trand name Chymodiactin) is a proteolytic enzyme isolated from the latex of papaya (Carica papaya). It is a medication used to treat herniated lower lumbar discs in the spine.[1] Chymopapain injections are normally given under local, rather than general, anaesthesia. The dose for a single intervertebral disc is 2 to 4 nanokatals, with a maximum dose per patient of 8 nanokatals.
The sale and distribution of chymopapain was discontinued in the United States on January 27, 2003.[2]
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Serious side effects from the use of chymopapain include anaphylaxis, paralysis of the legs, or death.[3]