CTTNBP2

Cortactin binding protein 2
Identifiers
Symbols CTTNBP2; C7orf8; CORTBP2; FLJ34229; KIAA1758; MGC104579; Orf4
External IDs OMIM609772 MGI1353467 HomoloGene14125 GeneCards: CTTNBP2 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 83992 30785
Ensembl ENSG00000077063 ENSMUSG00000000416
UniProt Q8WZ74 n/a
RefSeq (mRNA) NM_033427 NM_080285.1
RefSeq (protein) NP_219499 NP_525024.1
Location (UCSC) Chr 7:
117.35 – 117.51 Mb
Chr 6:
18.32 – 18.47 Mb
PubMed search [1] [2]

Cortactin-binding protein 2 is a protein that in humans is encoded by the CTTNBP2 gene.[1][2]

This gene encodes a protein with six ankyrin repeats and several proline-rich regions. A similar gene in rat interacts with a central regulator of the actin cytoskeleton.[2]

Interactions

CTTNBP2 has been shown to interact with RP6-213H19.1,[3] STRN,[3] STRN3,[3] MOBKL3[3] and PPP2CA.[3]

References

  1. ^ Cheung J, Petek E, Nakabayashi K, Tsui LC, Vincent JB, Scherer SW (Nov 2001). "Identification of the human cortactin-binding protein-2 gene from the autism candidate region at 7q31". Genomics 78 (1-2): 7–11. doi:10.1006/geno.2001.6651. PMID 11707066. 
  2. ^ a b "Entrez Gene: CTTNBP2 cortactin binding protein 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83992. 
  3. ^ a b c d e Goudreault, Marilyn; D'Ambrosio Lisa M, Kean Michelle J, Mullin Michael J, Larsen Brett G, Sanchez Amy, Chaudhry Sidharth, Chen Ginny I, Sicheri Frank, Nesvizhskii Alexey I, Aebersold Ruedi, Raught Brian, Gingras Anne-Claude (Jan. 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Mol. Cell Proteomics (United States) 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2621004. 

Further reading