CSNK1D

Casein kinase 1, delta

PDB rendering based on 1cki.
Identifiers
Symbols CSNK1D; HCKID
External IDs OMIM: 600864 MGI: 1355272 HomoloGene: 74841 GeneCards: CSNK1D Gene
EC number 2.7.11.1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 1453 104318
Ensembl ENSG00000141551 ENSMUSG00000025162
UniProt P48730 Q9DC28
RefSeq (mRNA) NM_001893.4 NM_027874
RefSeq (protein) NP_001884.2 NP_082150
Location (UCSC) Chr 17:
80.2 – 80.23 Mb		 Chr 11:
120.82 – 120.85 Mb
PubMed search [1] [2]

Casein kinase I isoform delta is an enzyme that in humans is encoded by the CSNK1D gene.[1]

This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene.[2]

Interactions

CSNK1D has been shown to interact with Gap junction protein, alpha 1.[3]

References

  1. ^ Fish KJ, Cegielska A, Getman ME, Landes GM, Virshup DM (Jul 1995). "Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family". J Biol Chem 270 (25): 14875–83. doi:10.1074/jbc.270.25.14875. PMID 7797465. 
  2. ^ "Entrez Gene: CSNK1D casein kinase 1, delta". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1453. 
  3. ^ Cooper, Cynthia D; Lampe Paul D (Nov. 2002). "Casein kinase 1 regulates connexin-43 gap junction assembly". J. Biol. Chem. (United States) 277 (47): 44962–8. doi:10.1074/jbc.M209427200. ISSN 0021-9258. PMID 12270943. 

Further reading