CLSTN1

Calsyntenin 1
Identifiers
Symbols CLSTN1; ALC-ALPHA; CDHR12; CSTN1; FLJ32258; KIAA0911; PIK3CD; XB31alpha; alcalpha1; alcalpha2
External IDs OMIM611321 MGI1929895 HomoloGene8814 GeneCards: CLSTN1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 22883 65945
Ensembl ENSG00000171603 ENSMUSG00000039953
UniProt O94985 Q8K103
RefSeq (mRNA) NM_001009566.1 NM_023051.4
RefSeq (protein) NP_001009566.1 NP_075538.1
Location (UCSC) Chr 1:
9.79 – 9.88 Mb
Chr 4:
148.96 – 149.02 Mb
PubMed search [1] [2]

Calsyntenin-1 is a protein that in humans is encoded by the CLSTN1 gene.[1][2]

Interactions

CLSTN1 has been shown to interact with APBA2[3][4] and Amyloid precursor protein.[4][3]

References

  1. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485. 
  2. ^ "Entrez Gene: CLSTN1 calsyntenin 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22883. 
  3. ^ a b Araki, Yoichi; Tomita Susumu, Yamaguchi Haruyasu, Miyagi Naomi, Sumioka Akio, Kirino Yutaka, Suzuki Toshiharu (Dec. 2003). "Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism". J. Biol. Chem. (United States) 278 (49): 49448–58. doi:10.1074/jbc.M306024200. ISSN 0021-9258. PMID 12972431. 
  4. ^ a b Araki, Yoichi; Miyagi Naomi, Kato Naoko, Yoshida Tomohiro, Wada Sachiyo, Nishimura Masaki, Komano Hiroto, Yamamoto Tohru, De Strooper Bart, Yamamoto Kazuo, Suzuki Toshiharu (Jun. 2004). "Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation". J. Biol. Chem. (United States) 279 (23): 24343–54. doi:10.1074/jbc.M401925200. ISSN 0021-9258. PMID 15037614. 

Further reading