CLDN4

Claudin 4
Identifiers
Symbols CLDN4; CPE-R; CPER; CPETR; CPETR1; WBSCR8; hCPE-R
External IDs OMIM602909 MGI1313314 HomoloGene1000 GeneCards: CLDN4 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 1364 12740
Ensembl ENSG00000189143 ENSMUSG00000047501
UniProt O14493 Q3UM35
RefSeq (mRNA) NM_001305.3 NM_009903.2
RefSeq (protein) NP_001296.1 NP_034033.1
Location (UCSC) Chr 7:
73.21 – 73.25 Mb
Chr 5:
135.42 – 135.42 Mb
PubMed search [1] [2]

Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins.

This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.[1]

References

Further reading