CLDN22

Claudin 22

Identifiers

CLDN22; CLDN21; FLJ51450

External IDs

HomoloGene: 82522 GeneCards: CLDN22 Gene

Gene Ontology
Molecular function	• structural molecule activity • identical protein binding
Cellular component	• plasma membrane • tight junction • integral to membrane • cell junction
Biological process	• calcium-independent cell-cell adhesion • cell junction assembly • cell-cell junction organization • tight junction assembly
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

ENSG00000177300

ENSMUSG00000038064

n/a

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 4:
184.24 – 184.24 Mb

Chr 8:
48.91 – 48.91 Mb

PubMed search

Claudin-22 is a protein that in humans is encoded by the CLDN22 gene.^[1] It belongs to the group of claudins.

References

^ "Entrez Gene: CLDN22 claudin 22". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53842.

Further reading

González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins.". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets.". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions.". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport.". Traffic 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
Kniesel U, Wolburg H (2000). "Tight junctions of the blood-brain barrier.". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Katoh M, Katoh M (2004). "CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family.". Int. J. Mol. Med. 11 (6): 683–9. PMID 12736707.